https://academic.oup.com/ajcn/article/91/3/535/4597110?links=false
Conclusions: A meta-analysis of prospective epidemiologic studies showed that there is no significant evidence for concluding that dietary saturated fat is associated with an increased risk of CHD or CVD.
Patty W Siri-Tarino, Qi Sun, Frank B Hu, Ronald M Krauss, Meta-analysis of prospective cohort studies evaluating the association of saturated fat with cardiovascular disease, The American Journal of Clinical Nutrition, Volume 91, Issue 3, March 2010, Pages 535–546, https://doi.org/10.3945/ajcn.2009.27725
Visar inlägg med etikett Saturated Fat. Visa alla inlägg
Visar inlägg med etikett Saturated Fat. Visa alla inlägg
torsdag 5 december 2019
onsdag 17 januari 2018
Saturated fat does not clog the arteries: coronary heart disease is a chronic inflammatory condition, the risk of which can be effectively reduced from healthy lifestyle interventions | British Journal of Sports Medicine
http://bjsm.bmj.com/content/51/15/1111
"Coronary artery disease pathogenesis and treatment urgently requires a paradigm shift. Despite popular belief among doctors and the public, the conceptual model of dietary saturated fat clogging a pipe is just plain wrong."
"Coronary artery disease pathogenesis and treatment urgently requires a paradigm shift. Despite popular belief among doctors and the public, the conceptual model of dietary saturated fat clogging a pipe is just plain wrong."
Saturated fat does not clog the arteries: coronary heart disease is a chronic inflammatory condition, the risk of which can be effectively reduced from healthy lifestyle interventions
söndag 25 september 2016
Meta-analysis of prospective cohort studies evaluating the association of saturated fat with cardiovascular disease. - PubMed - NCBI
https://www.ncbi.nlm.nih.gov/m/pubmed/20071648/?i=3&from=Siri-Tarino%20PW,%20Sun%20Q,%20Hu%20FB,%20Krauss%20RM
"CONCLUSIONS: A meta-analysis of prospective epidemiologic studies showed that there is no significant evidence for concluding that dietary saturated fat is associated with an increased risk of CHD or CVD. More data are needed to elucidate whether CVD risks are likely to be influenced by the specific nutrients used to replace saturated fat."
Siri-Tarino PW, Sun Q, Hu FB,
Krauss RM. Meta-analysis of prospective cohort studies evaluating the
association of saturated fat with cardiovascular disease. Am J Clin
Nutr 2010;91:535-46.
"CONCLUSIONS: A meta-analysis of prospective epidemiologic studies showed that there is no significant evidence for concluding that dietary saturated fat is associated with an increased risk of CHD or CVD. More data are needed to elucidate whether CVD risks are likely to be influenced by the specific nutrients used to replace saturated fat."
Siri-Tarino PW, Sun Q, Hu FB,
Krauss RM. Meta-analysis of prospective cohort studies evaluating the
association of saturated fat with cardiovascular disease. Am J Clin
Nutr 2010;91:535-46.
tisdag 16 juni 2015
Effects of Step-Wise Increases in Dietary Carbohydrate on Circulating Saturated Fatty Acids and Palmitoleic Acid in Adults with Metabolic Syndrome
http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0113605
Abstract
Recent meta-analyses have found no association between heart disease and dietary saturated fat; however, higher proportions of plasma saturated fatty acids (SFA) predict greater risk for developing type-2 diabetes and heart disease. These observations suggest a disconnect between dietary saturated fat and plasma SFA, but few controlled feeding studies have specifically examined how varying saturated fat intake across a broad range affects circulating SFA levels. Sixteen adults with metabolic syndrome (age 44.9±9.9 yr, BMI 37.9±6.3 kg/m2) were fed six 3-wk diets that progressively increased carbohydrate (from 47 to 346 g/day) with concomitant decreases in total and saturated fat. Despite a distinct increase in saturated fat intake from baseline to the low-carbohydrate diet (46 to 84 g/day), and then a gradual decrease in saturated fat to 32 g/day at the highest carbohydrate phase, there were no significant changes in the proportion of total SFA in any plasma lipid fractions. Whereas plasma saturated fat remained relatively stable, the proportion of palmitoleic acid in plasma triglyceride and cholesteryl ester was significantly and uniformly reduced as carbohydrate intake decreased, and then gradually increased as dietary carbohydrate was re-introduced. The results show that dietary and plasma saturated fat are not related, and that increasing dietary carbohydrate across a range of intakes promotes incremental increases in plasma palmitoleic acid, a biomarker consistently associated with adverse health outcomes.
Citation: Volk BM, Kunces LJ, Freidenreich DJ, Kupchak BR, Saenz C, Artistizabal JC, et al. (2014) Effects of Step-Wise Increases in Dietary Carbohydrate on Circulating Saturated Fatty Acids and Palmitoleic Acid in Adults with Metabolic Syndrome. PLoS ONE 9(11): e113605. doi:10.1371/journal.pone.0113605
Abstract
Recent meta-analyses have found no association between heart disease and dietary saturated fat; however, higher proportions of plasma saturated fatty acids (SFA) predict greater risk for developing type-2 diabetes and heart disease. These observations suggest a disconnect between dietary saturated fat and plasma SFA, but few controlled feeding studies have specifically examined how varying saturated fat intake across a broad range affects circulating SFA levels. Sixteen adults with metabolic syndrome (age 44.9±9.9 yr, BMI 37.9±6.3 kg/m2) were fed six 3-wk diets that progressively increased carbohydrate (from 47 to 346 g/day) with concomitant decreases in total and saturated fat. Despite a distinct increase in saturated fat intake from baseline to the low-carbohydrate diet (46 to 84 g/day), and then a gradual decrease in saturated fat to 32 g/day at the highest carbohydrate phase, there were no significant changes in the proportion of total SFA in any plasma lipid fractions. Whereas plasma saturated fat remained relatively stable, the proportion of palmitoleic acid in plasma triglyceride and cholesteryl ester was significantly and uniformly reduced as carbohydrate intake decreased, and then gradually increased as dietary carbohydrate was re-introduced. The results show that dietary and plasma saturated fat are not related, and that increasing dietary carbohydrate across a range of intakes promotes incremental increases in plasma palmitoleic acid, a biomarker consistently associated with adverse health outcomes.
Citation: Volk BM, Kunces LJ, Freidenreich DJ, Kupchak BR, Saenz C, Artistizabal JC, et al. (2014) Effects of Step-Wise Increases in Dietary Carbohydrate on Circulating Saturated Fatty Acids and Palmitoleic Acid in Adults with Metabolic Syndrome. PLoS ONE 9(11): e113605. doi:10.1371/journal.pone.0113605
torsdag 25 december 2014
Dietary fats, carbohydrate, and progression of coronary atherosclerosis in postmenopausal women
Dietary fats, carbohydrate, and progression of coronary atherosclerosis in postmenopausal women
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1270002/
Mozaffarian D, Rimm
EB, Herrington DM. Dietary fats, carbohydrate, and progression of coronary
atherosclerosis in postmenopausal women. The American journal of clinical
nutrition 2004;80(5):1175-1184.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1270002/EB, Herrington DM. Dietary fats, carbohydrate, and progression of coronary
atherosclerosis in postmenopausal women. The American journal of clinical
nutrition 2004;80(5):1175-1184.
Abstract
Background:
The influence of diet on atherosclerotic progression is not well established, particularly in postmenopausal women, in whom risk factors for progression may differ from those for men.
The influence of diet on atherosclerotic progression is not well established, particularly in postmenopausal women, in whom risk factors for progression may differ from those for men.
Objective:
The objective was to investigate associations between dietary macronutrients and progression of coronary atherosclerosis among postmenopausal women.
The objective was to investigate associations between dietary macronutrients and progression of coronary atherosclerosis among postmenopausal women.
Design:
Quantitative coronary angiography was performed at baseline and after a mean follow-up of 3.1 y in 2243 coronary segments in 235 postmenopausal women with established coronary heart disease. Usual dietary intake was assessed at baseline.
Quantitative coronary angiography was performed at baseline and after a mean follow-up of 3.1 y in 2243 coronary segments in 235 postmenopausal women with established coronary heart disease. Usual dietary intake was assessed at baseline.
Results:
The mean (±SD) total fat intake was 25 ± 6% of energy. In multivariate analyses, a higher saturated fat intake was associated with a smaller decline in mean minimal coronary diameter (P = 0.001) and less progression of coronary stenosis (P =0.002) during follow-up. Compared with a 0.22-mm decline in the lowest quartile of intake, there was a 0.10-mm decline in the second quartile (P = 0.002), a 0.07-mm decline in the third quartile (P = 0.002), and no decline in the fourth quartile (P <0.001); P for trend =0.001. This inverse association was more pronounced among women with lower monounsaturated fat (P for interaction =0.04) and higher carbohydrate (P for interaction =0.004) intakes and possibly lower total fat intake (P for interaction =0.09). Carbohydrate intake was positively associated with atherosclerotic progression (P=0.001), particularly when the glycemic index was high. Polyunsaturated fat intake was positively associated with progression when replacing other fats (P = 0.04) but not when replacing carbohydrate or protein. Monoun-saturated and total fat intakes were not associated with progression.
The mean (±SD) total fat intake was 25 ± 6% of energy. In multivariate analyses, a higher saturated fat intake was associated with a smaller decline in mean minimal coronary diameter (P = 0.001) and less progression of coronary stenosis (P =0.002) during follow-up. Compared with a 0.22-mm decline in the lowest quartile of intake, there was a 0.10-mm decline in the second quartile (P = 0.002), a 0.07-mm decline in the third quartile (P = 0.002), and no decline in the fourth quartile (P <0.001); P for trend =0.001. This inverse association was more pronounced among women with lower monounsaturated fat (P for interaction =0.04) and higher carbohydrate (P for interaction =0.004) intakes and possibly lower total fat intake (P for interaction =0.09). Carbohydrate intake was positively associated with atherosclerotic progression (P=0.001), particularly when the glycemic index was high. Polyunsaturated fat intake was positively associated with progression when replacing other fats (P = 0.04) but not when replacing carbohydrate or protein. Monoun-saturated and total fat intakes were not associated with progression.
Conclusions:
In postmenopausal women with relatively low total fat intake, a greater saturated fat intake is associated with less progression of coronary atherosclerosis, whereas carbohydrate intake is associated with a greater progression.
In postmenopausal women with relatively low total fat intake, a greater saturated fat intake is associated with less progression of coronary atherosclerosis, whereas carbohydrate intake is associated with a greater progression.
tisdag 9 september 2014
Nina Teicholz on Saturated Fats & the Soft Science on Fat – #149 | The Bulletproof Executive
Nina Teicholz on Saturated Fats & the Soft Science on Fat – #149 | The Bulletproof Executive
What You’ll Hear
- 0:07 – Cool Fact of the Day!
- 0:45 – Welcome Nina Teicholz
- 1:51 – Fat-powered astronauts and athletes
- 3:26 – Nina’s journey into studying fat
- 6:10 – Exploring the story of how fat got demonized
- 9:50 – Why our working hypothesis of health isn’t working
- 15:04 – The role of food companies in starting the fat scare
- 21:04 – A story of failed science and fat
- 27:15 – Problems with low-fat diets
- 32:56 – The health benefits of saturated fats
- 37:46 – The dangers of oxidized oils
- 43:38 – Ketogenic diets
- 47:02 – Low-fat foods in schools
- 52:15 – The slandering of tropical oils
- 53:56 – Are the food companies getting an unfair bad rap?
- 55:45 – The dietary double standard against fat
- 59:21 – Top three recommendations for kicking more ass and being Bulletproof!
tisdag 2 september 2014
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