tisdag 3 september 2019

Nutrients | Free Full-Text | The Dietary Intake of Wheat and other Cereal Grains and Their Role in Inflammation | HTML

https://www.mdpi.com/2072-6643/5/3/771/htm


In this review we discuss evidence from in vitroin vivo and human intervention studies that describe how the consumption of wheat, but also other cereal grains, can contribute to the manifestation of chronic inflammation and autoimmune diseases by increasing intestinal permeability and initiating a pro-inflammatory immune response


De Punder, K. & Pruimboom, L. (2013). The Dietary Intake of Wheat and other Cereal Grains and Their Role in Inflammation. Nutrients, 5(3). doi:10.3390/nu5030771

söndag 11 augusti 2019

Egg consumption, cholesterol intake, and risk of incident stroke in men: the Kuopio Ischaemic Heart Disease Risk Factor Study | The American Journal of Clinical Nutrition | Oxford Academic

https://academic.oup.com/ajcn/article-abstract/110/1/169/5490306


Conclusion: Neither egg nor cholesterol intakes were associated with stroke risk in this cohort, regardless of apoE phenotype.


Anna M Abdollahi, Heli E K Virtanen, Sari Voutilainen, Sudhir Kurl, Tomi-Pekka Tuomainen, Jukka T Salonen, Jyrki K Virtanen, Egg consumption, cholesterol intake, and risk of incident stroke in men: the Kuopio Ischaemic Heart Disease Risk Factor Study, The American Journal of Clinical Nutrition, Volume 110, Issue 1, July 2019, Pages 169–176, https://doi.org/10.1093/ajcn/nqz066

lördag 13 juli 2019

Ketogenic diet activates protective γδ T cell responses against influenza virus infection | The Journal of Immunology

https://www.jimmunol.org/content/202/1_Supplement/62.7.abstract


"Ketogenic diet (KD) feeding resulted in an expansion of γδ T cells in the lung that improved barrier functions, thereby enhancing anti-viral resistance."
...
"Therefore, KD mediated immune-metabolic integration represents a viable avenue towards preventing or alleviating influenza disease."

Goldberg, E. L., Molony, R., Sidorov, S., Kudo, E., Dixit, V. D. & Iwasaki, A. (2019). Ketogenic diet activates protective γδ T cell responses against influenza virus infection. The Journal of Immunology, 202(1 Supplement), ss. 62.7-62.7. 

söndag 30 juni 2019

Low-carb diet may reduce diabetes risk independent of weight loss: Researchers report reversal of metabolic syndrome in some cases -- ScienceDaily

https://www.sciencedaily.com/releases/2019/06/190620100036.htm


Low-carb diet may reduce diabetes risk independent of weight loss: Researchers report reversal of metabolic syndrome in some cases


Ohio State University. (2019, June 20). Low-carb diet may reduce diabetes risk independent of weight loss: Researchers report reversal of metabolic syndrome in some cases. ScienceDaily. Retrieved June 30, 2019 from www.sciencedaily.com/releases/2019/06/190620100036.htm

fredag 24 maj 2019

Sugary Beverage Consumption and All-Cause Mortality

https://www.jwatch.org/na49179/2019/05/23/sugary-beverage-consumption-and-all-cause-mortality?ijkey=7T5HpAUWU


"Mean sugary beverage consumption was 8.4% of total calories, split roughly equally between sugar-sweetened beverages and 100% fruit juice (which are essentially identical in sugar content)."


"For example, high consumption of sugary beverages" ...

"was associated with 44% higher risk for CHD-related death. The relative risk for all-cause mortality increased by 24% for every additional 12-ounce consumption of 100% fruit juice."


Collin LJ et al. Association of sugary beverage consumption with mortality risk in US adults: A secondary analysis of data from the REGARDS study. JAMA Netw Open 2019 May 3; 2:e193121. (https://doi.org/10.1001/jamanetworkopen.2019.3121)






onsdag 22 maj 2019

Nutrients | Potential Protective Mechanisms of Ketone Bodies in Migraine Prevention | HTML

https://www.mdpi.com/2072-6643/11/4/811/htm

"An increasing amount of evidence suggests that migraines are a response to a cerebral energy deficiency or oxidative stress levels that exceed antioxidant capacity. The ketogenic diet (KD), a diet mimicking fasting that leads to the elevation of ketone bodies (KBs), is a therapeutic intervention targeting cerebral metabolism that has recently shown great promise in the prevention of migraines."


Gross, E. C., Klement, R. J., Schoenen, J., D’Agostino, D. P. & Fischer, D. (2019). Potential Protective Mechanisms of Ketone Bodies in Migraine Prevention. Nutrients, 11(4), s. 811.

lördag 20 april 2019

Anticatabolic Effects of Ketone Bodies in Skeletal Muscle

https://www.sciencedirect.com/science/article/pii/S1043276019300128



"Anticatabolic effects of β-hydroxybutyrate have recently been demonstrated in human skeletal muscle under inflammatory insult, thereby expanding upon the wide-ranging therapeutic applications of nutritional ketosis."



Koutnik, A. P., D’Agostino, D. P. & Egan, B. (2019). Anticatabolic Effects of Ketone Bodies in Skeletal Muscle. Trends in Endocrinology & Metabolism, 30(4), ss. 227-229. doi:https://doi.org/10.1016/j.tem.2019.01.006

måndag 25 mars 2019

Prenatal and infant exposure to ambient pesticides and autism spectrum disorder in children: population based case-control study | The BMJ

https://www.bmj.com/content/364/bmj.l962


Conclusion: Findings suggest that an offspring’s risk of autism spectrum disorder increases following prenatal exposure to ambient pesticides within 2000 m of their mother’s residence during pregnancy, compared with offspring of women from the same agricultural region without such exposure. Infant exposure could further increase risks for autism spectrum disorder with comorbid intellectual disability.


von Ehrenstein, O. S., Ling, C., Cui, X., Cockburn, M., Park, A. S., Yu, F., Wu, J. & Ritz, B. (2019). Prenatal and infant exposure to ambient pesticides and autism spectrum disorder in children: population based case-control study. BMJ, 364. 

fredag 15 mars 2019

No effect of 600 grams fruit and vegetables per day on oxidative DNA damage and repair in healthy nonsmokers. - PubMed - NCBI

https://www.ncbi.nlm.nih.gov/m/pubmed/14578137/


"In several epidemiological studies, high intakes of fruits and vegetables have been associated with a lower incidence of cancer. Theoretically, intake of antioxidants by consumption of fruits and vegetables should protect against reactive oxygen species and decrease the formation of oxidative DNA damage."

...

"Our results show that after 24 days of complete depletion of fruits and vegetables, or daily ingestion of 600 g of fruit and vegetables, or the corresponding amount of vitamins and minerals, the level of oxidative DNA damage was unchanged."


Cancer Epidemiol Biomarkers Prev. 2003 Oct;12(10):1016-22.

Meat intake and cause-specific mortality: a pooled analysis of Asian prospective cohort studies

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3778858/


Conclusions: Ecological data indicate an increase in meat intake in Asian countries; however, our pooled analysis did not provide evidence of a higher risk of mortality for total meat intake and provided evidence of an inverse association with red meat, poultry, and fish/seafood. Red meat intake was inversely associated with CVD (cardiovascular disease) mortality in men and with cancer mortality in women in Asian countries.


Lee JE, McLerran DF, Rolland B, et al. Meat intake and cause-specific mortality: a pooled analysis of Asian prospective cohort studies. Am J Clin Nutr. 2013;98(4):1032-41.

onsdag 6 mars 2019

Infection control for norovirus

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4624335/


"Ready-to-eat foods (such as leafy greens) and foods handled after cooking are the most frequently identified products associated with outbreaks"

"Leafy vegetables, fruits, and shellfish, all of which are commonly consumed raw or undercooked, are the food commodities most commonly reported as the cause of foodborne norovirus outbreaks"

"Norwalk virus seeded into ground water for at least 61 days was still able to infect human volunteers"


Barclay L, Park GW, Vega E, et al. Infection control for norovirus. Clin Microbiol Infect. 2014;20(8):731-40.

Human norovirus transmission and evolution in a changing world. - PubMed - NCBI

https://www.ncbi.nlm.nih.gov/pubmed/27211790


"the globalization of the food industry, which enables large norovirus outbreaks to occur on an international scale."

"studies have shown that approximately 7% of foodborne outbreaks of noroviruses are part of an international event with a common source. Globally, noroviruses rank among the top causes of foodborne disease"


de Graaf, M., van Beek, J. & Koopmans, M. P. (2016). Human norovirus transmission and evolution in a changing world. Nat Rev Microbiol, 14(7), ss. 421-433. DOI:10.1038/nrmicro.2016.48

fredag 22 februari 2019

Nutritional Ketosis Alters Fuel Preference and Thereby Endurance Performance in Athletes: Cell Metabolism

https://www.cell.com/cell-metabolism/fulltext/S1550-4131(16)30355-2



"In five separate studies of 39 high-performance athletes, we show how this unique metabolic state improves physical endurance by altering fuel competition for oxidative respiration."



DOI: https://doi.org/10.1016/j.cmet.2016.07.010

Ketone Bodies as a Therapeutic Strategy for Heart Failure: Biophysical Journal

https://www.cell.com/biophysj/pdf/S0006-3495(18)31300-6.pdf


"Taken together, we conclude that the shift to ketone body oxidation in heart failure is adaptive and that strategies to increase myocardial ketone body delivery show promise for the treatment of heart failure."


DOI: https://doi.org/10.1016/j.bpj.2018.11.035