fredag 26 juni 2015

3 studies about Vitamin C and Cancer




Cameron E, Pauling L. Supplemental ascorbate in the supportive treatment of cancer: Prolongation of survival times in terminal human cancer. Proceedings of the National Academy of Sciences of the United States of America. 1976;73(10):3685-3689.
PMCID: PMC431183
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC431183/


Cameron E, Pauling L. Supplemental ascorbate in the supportive treatment of cancer: Reevaluation of prolongation of survival times in terminal human cancer.Proceedings of the National Academy of Sciences of the United States of America. 1978;75(9):4538-4542.
PMCID: PMC336151
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC336151/


Cabanillas F. Vitamin C and cancer: what can we conclude--1,609 patients and
33 years later? P R Health Sci J. 2010 Sep;29(3):215-7. Review. PubMed
PMID: 20799507.
http://www.ncbi.nlm.nih.gov/pubmed/20799507



tisdag 16 juni 2015

Effects of Step-Wise Increases in Dietary Carbohydrate on Circulating Saturated Fatty Acids and Palmitoleic Acid in Adults with Metabolic Syndrome

http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0113605



Abstract


Recent meta-analyses have found no association between heart disease and dietary saturated fat; however, higher proportions of plasma saturated fatty acids (SFA) predict greater risk for developing type-2 diabetes and heart disease. These observations suggest a disconnect between dietary saturated fat and plasma SFA, but few controlled feeding studies have specifically examined how varying saturated fat intake across a broad range affects circulating SFA levels. Sixteen adults with metabolic syndrome (age 44.9±9.9 yr, BMI 37.9±6.3 kg/m2) were fed six 3-wk diets that progressively increased carbohydrate (from 47 to 346 g/day) with concomitant decreases in total and saturated fat. Despite a distinct increase in saturated fat intake from baseline to the low-carbohydrate diet (46 to 84 g/day), and then a gradual decrease in saturated fat to 32 g/day at the highest carbohydrate phase, there were no significant changes in the proportion of total SFA in any plasma lipid fractions. Whereas plasma saturated fat remained relatively stable, the proportion of palmitoleic acid in plasma triglyceride and cholesteryl ester was significantly and uniformly reduced as carbohydrate intake decreased, and then gradually increased as dietary carbohydrate was re-introduced. The results show that dietary and plasma saturated fat are not related, and that increasing dietary carbohydrate across a range of intakes promotes incremental increases in plasma palmitoleic acid, a biomarker consistently associated with adverse health outcomes.



Citation: Volk BM, Kunces LJ, Freidenreich DJ, Kupchak BR, Saenz C, Artistizabal JC, et al. (2014) Effects of Step-Wise Increases in Dietary Carbohydrate on Circulating Saturated Fatty Acids and Palmitoleic Acid in Adults with Metabolic Syndrome. PLoS ONE 9(11): e113605. doi:10.1371/journal.pone.0113605

fredag 12 juni 2015

Vitamin B status in patients with type 2 diabetes mellitus with and without incipient nephropathy. - PubMed - NCBI

http://www.ncbi.nlm.nih.gov/pubmed/25458341













Vitamin B status in patients with type 2 diabetes mellitus with and without incipient nephropathy.

Nix WA, Zirwes R, Bangert V, Kaiser RP, Schilling M, Hostalek U, Obeid R.

Diabetes Res Clin Pract. 2015 Jan;107(1):157-65. doi: 10.1016/j.diabres.2014.09.058. Epub 2014 Oct 8.

PMID: 25458341

http://www.ncbi.nlm.nih.gov/pubmed/25458341

onsdag 3 juni 2015

Antitumor activity of astaxanthin and its mode of action. - PubMed - NCBI

http://www.ncbi.nlm.nih.gov/pubmed/10798217










Antitumor activity of astaxanthin and its mode of action.
Jyonouchi H, Sun S, Iijima K, Gross MD.
Nutr Cancer. 2000;36(1):59-65.
PMID: 10798217