onsdag 17 januari 2018

Saturated fat does not clog the arteries: coronary heart disease is a chronic inflammatory condition, the risk of which can be effectively reduced from healthy lifestyle interventions | British Journal of Sports Medicine

http://bjsm.bmj.com/content/51/15/1111



"Coronary artery disease pathogenesis and treatment urgently requires a paradigm shift. Despite popular belief among doctors and the public, the conceptual model of dietary saturated fat clogging a pipe is just plain wrong."




Malhotra ARedberg RFMeier P
Saturated fat does not clog the arteries: coronary heart disease is a chronic inflammatory condition, the risk of which can be effectively reduced from healthy lifestyle interventions


Evidence That Intermittent, Excessive Sugar Intake Causes Endogenous Opioid Dependence - Colantuoni - 2002 - Obesity - Wiley Online Library

http://onlinelibrary.wiley.com/doi/10.1038/oby.2002.66/abstract;jsessionid=53655E300DCC6F52F425701CBE72C85E.f02t04


Discussion: Repeated, excessive intake of sugar created a state in which an opioid antagonist caused behavioral and neurochemical signs of opioid withdrawal. The indices of anxiety and DA/ACh imbalance were qualitatively similar to withdrawal from morphine or nicotine, suggesting that the rats had become sugar-dependent.


Colantuoni, C., Rada, P., McCarthy, J., Patten, C., Avena, N. M., Chadeayne, A. and Hoebel, B. G. (2002), Evidence That Intermittent, Excessive Sugar Intake Causes Endogenous Opioid Dependence. Obesity Research, 10: 478–488. doi:10.1038/oby.2002.66