måndag 25 mars 2019

Prenatal and infant exposure to ambient pesticides and autism spectrum disorder in children: population based case-control study | The BMJ

https://www.bmj.com/content/364/bmj.l962


Conclusion: Findings suggest that an offspring’s risk of autism spectrum disorder increases following prenatal exposure to ambient pesticides within 2000 m of their mother’s residence during pregnancy, compared with offspring of women from the same agricultural region without such exposure. Infant exposure could further increase risks for autism spectrum disorder with comorbid intellectual disability.


von Ehrenstein, O. S., Ling, C., Cui, X., Cockburn, M., Park, A. S., Yu, F., Wu, J. & Ritz, B. (2019). Prenatal and infant exposure to ambient pesticides and autism spectrum disorder in children: population based case-control study. BMJ, 364. 

fredag 15 mars 2019

No effect of 600 grams fruit and vegetables per day on oxidative DNA damage and repair in healthy nonsmokers. - PubMed - NCBI

https://www.ncbi.nlm.nih.gov/m/pubmed/14578137/


"In several epidemiological studies, high intakes of fruits and vegetables have been associated with a lower incidence of cancer. Theoretically, intake of antioxidants by consumption of fruits and vegetables should protect against reactive oxygen species and decrease the formation of oxidative DNA damage."

...

"Our results show that after 24 days of complete depletion of fruits and vegetables, or daily ingestion of 600 g of fruit and vegetables, or the corresponding amount of vitamins and minerals, the level of oxidative DNA damage was unchanged."


Cancer Epidemiol Biomarkers Prev. 2003 Oct;12(10):1016-22.

Meat intake and cause-specific mortality: a pooled analysis of Asian prospective cohort studies

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3778858/


Conclusions: Ecological data indicate an increase in meat intake in Asian countries; however, our pooled analysis did not provide evidence of a higher risk of mortality for total meat intake and provided evidence of an inverse association with red meat, poultry, and fish/seafood. Red meat intake was inversely associated with CVD (cardiovascular disease) mortality in men and with cancer mortality in women in Asian countries.


Lee JE, McLerran DF, Rolland B, et al. Meat intake and cause-specific mortality: a pooled analysis of Asian prospective cohort studies. Am J Clin Nutr. 2013;98(4):1032-41.

onsdag 6 mars 2019

Infection control for norovirus

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4624335/


"Ready-to-eat foods (such as leafy greens) and foods handled after cooking are the most frequently identified products associated with outbreaks"

"Leafy vegetables, fruits, and shellfish, all of which are commonly consumed raw or undercooked, are the food commodities most commonly reported as the cause of foodborne norovirus outbreaks"

"Norwalk virus seeded into ground water for at least 61 days was still able to infect human volunteers"


Barclay L, Park GW, Vega E, et al. Infection control for norovirus. Clin Microbiol Infect. 2014;20(8):731-40.

Human norovirus transmission and evolution in a changing world. - PubMed - NCBI

https://www.ncbi.nlm.nih.gov/pubmed/27211790


"the globalization of the food industry, which enables large norovirus outbreaks to occur on an international scale."

"studies have shown that approximately 7% of foodborne outbreaks of noroviruses are part of an international event with a common source. Globally, noroviruses rank among the top causes of foodborne disease"


de Graaf, M., van Beek, J. & Koopmans, M. P. (2016). Human norovirus transmission and evolution in a changing world. Nat Rev Microbiol, 14(7), ss. 421-433. DOI:10.1038/nrmicro.2016.48